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Heartflow One turns a coronary CT angiography (CCTA) scan into a personalized 3D model of the heart using AI. Clinicians use it to detect coronary artery disease, measure plaque, assess blood flow, and pre-plan PCI. Scans are sent securely to Heartflow for analysis, and results can be delivered into PACS and EMR systems. The company reports a median turnaround time of 90 minutes. Heartflow says more than 1,800 institutions use it, and it cites over 625 peer-reviewed publications. It is commercially available in the US, with select functionality in the EU, UK, Japan and Canada.

Decisive Coronary Care. See CAD. Manage for life.

Key features

  • Roadmap Analysis: AI-assisted reading of CCTA for consistent results across readers and early detection of CAD
  • FFRCT Analysis: assesses blood flow anywhere in the coronary tree to determine the benefit of revascularization
  • Plaque Analysis: quantifies and characterizes plaque to inform risk and manage disease
  • Plaque Staging: stages Total Plaque Volume (TPV) for an actionable assessment of CAD
  • PCI Navigator: pre-plans PCI with a patient-specific 3D model showing anatomy, plaque composition and lesion-specific physiology
  • PACS/EMR delivery: results can be delivered automatically into PACS and EMR (optional; FFRCT and Plaque results appear only if requested)
  • Heartflow Support: training, coding and reimbursement help, technology integration, peer education, and clinical and technical case support

Strengths

  • Anatomy, plaque, physiology and PCI planning all come from a single CCTA scan
  • Stated median turnaround of 90 minutes
  • More than 625 peer-reviewed publications (vendor-reported)
  • Used by more than 1,800 institutions (vendor-reported)
  • FDA clearances listed on the company timeline (FFRCT 2014, Roadmap and Plaque 2022, Next Gen Plaque 2025)
  • Optional PACS and EMR delivery
  • Dedicated clinical, operational, technical and reimbursement support

Best for

  • Cardiologist or cardiac imaging team building or scaling a CCTA program
  • Hospital or health system evaluating patients with suspected coronary artery disease
  • Interventional cardiologist planning PCI

Integrations

  • PACS (native, deep, system)
  • EMR (native, deep, system)

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